Department of Health Research, Ministry of Health and Family Welfare, Government of India
स्वास्थ्य अनुसंधान विभाग, स्वास्थ्य और परिवार कल्याण मंत्रालय, भारत सरकार
WHO Collaborating Centre For Research and Training On Diarrhoeal Diseases
Dr. Shanta Dutta MD, Ph.D., Scientist G, National Institute of Cholera and Enteric Diseases, Kolkata, is a clinical microbiologist and a medical research scientist. After graduated in Medicine from Calcutta National Medical College under the University of Calcutta in 1986, she completed postgraduation in Medical Microbiology from the Kasturba Medical College, Manipal, Mangalore University in 1992. She has joined NICED, a constituent Institute of the Indian Council of Medical Research (ICMR) and a WHO Collaborating Centre for Research and Training in Enteric Diseases, in August 1994 and presently holding the post of Scientist G (Director) in the Division of Bacteriology.
She was awarded with RONPAKU fellowship of JSPS (Japanese Society for Promotion of Science) during 2001-2005 by Dept. of Science and Technology, M/O Science and Technology, Govt. of India (Indian counterpart) and was conferred with Ph.D. Degree from Kyushu University, Japan in 2006 under this program. During this fellowship she gained experience of working on virulence, antimicrobial resistance and molecular epidemiology of enteric bacterial pathogens in the Department of Bacteriology, Kyushu University, Fukuoka, Japan. She was selected to participate in the Advanced WHO course on "Immunology, Vaccinology, Biotechnology and Biosafety applied to Infectious Diseases", held in Lausanne, Switzerland during Sept. - Oct., 1996. She has participated in the International course of laboratory diagnosis of Diarrhoeal Diseases, at ICDDR,B Dacca, Bangladesh during August 2002.She has been elected as a member of the National Academy of Medical Sciences (India) (MAMS) in the year 2013 In recognition of significant contribution for the advancement of medical Sciences.She is actively involved in research, training and teaching of the microbiological aspect of enteric diseases including diarrhea, enteric fever, water bacteriology. She has interests in exploring antimicrobial resistance of enteric pathogens, mechanism of drug resistance and antibacterial activity of bioactive molecules derived from herbal products. She has worked as principal investigator in a number of intramural and extramural funded projects. She supported the microbiology component of the studies pertaining to other divisions like epidemiology and clinical as a co-investigator and responsible for timely feedback of results to the concerned divisions. She took part in the vaccine trial of Typhoid vaccine (Vi polysaccharide vaccine), disease burden study of typhoid, randomized control clinical trials on usefulness of probiotics in acute diarrhea, role of vit A, micronutrients in acute watery diarrhoea. She acted as an expert in the UNICEF funded project on "Drinking water quality monitoring by H2S KIT" and participated as the nodal person in the multi-centric study on evaluation and operational research of the kit. On ICMR request, she was also involved in the evaluation of solar disinfection method of drinking water in rural household (SODIS).
She has published a number (>65) of original research articles in peer-reviewed national and international journals in the area of Clinical Microbiology, Molecular Epidemiology and Pathogenesis of enteric pathogens, water bacteriology including book chapters. She attended various national and international conferences and presented papers on her research studies. She served as an invited reviewer of a number of national and international reputed journals like Journal of Antimicrobial Chemotherapy, Diagnostic Microbiology Infectious Diseases, Journal of Medical Microbiology, PloS One, BMC infectious Diseases, International Journal of Infectious Diseases, WHO Guidelines. She has been invited to become editorial international board member of various publishing agencies.
Name | Dr. Shanta Dutta |
---|---|
Designation | Director & Scientist G |
Date of joining ICMR | 3rd August, 1994 |
Date of joining present post | 12th July, 2016 |
Discipline | Clinical / Public Health Microbiology |
Division | Bacteriology |
Specialization | Medical Microbiology with special reference to enteric diseases |
drshantadutta@gmail.com ,
shanta.niced@icmr.gov.in , shanta1232001@gmail.com |
|
Academic Qualification | |
Graduation | MBBS, Calcutta Univ., India, Nov. 1986 |
Post Graduation | MD (Medical Microbiology), Mangalore Univ., India, Dec. 1992 |
Doctoral | Ph.D. (Medical science), Kyushu University, Japan, Mar 2006 |
Dr. Dutta has more than 26 years of research experience in the field of enteric/ diarrheal diseases. She is actively involved in field based epidemiological studies as well as laboratory based molecular studies with the bacterial isolates, both clinical and environmental origin, w.r.t. their antimicrobial resistance marker, plasmid profiles, virulence markers and sequence based molecular subtyping etc. She has acted as an invited reviewer of a number of international peer reviewed journals and as a project reviewer of national and international funding agencies. She has published more than 250 articles in the high impact journals. Attended national and international conferences and delivered her views as consultants/ members of steering committee/advisory committee/ of Research Review committee/ of national and international research forum. She is the member of Technical Working Group (TWG) of the Global Task Force of Cholera Control Committee (GTFCC) and participated in GTFCC WHO meetings addressing the cholera control at the national level. Conducted collaborative projects as Principal site investigators in a number of studies funded by national/international agencies. She is invited to become internal/ external examiner for Ph.D. thesis evaluation, to impart training to the post graduate students of various national universities to complete their projects. She acted as the guide of Ph.D. students to accomplish their Ph.D. thesis and publish their results in peer reviewed high impact journals. Involved in teaching of Microbiology to undergraduate and post graduate students of both medical and non-medical curriculum.
The area of her research work focuses on both applied and basic aspects of enteric diseases and enteric pathogens with special reference to entero-virulent Escherichia coli, Shigella, Salmonella and V. cholerae species. Studying phenotypic and genetic characters of various enteric bacteria and analyzing the results are her major research interest. In view of the emerging issues of antimicrobial resistance, exploring antibacterial activity of herbal extracts is another area, where she puts in efforts, which might lead to some new product with strong antibacterial potential. Other research interests include bacterial population genetics, evaluation of new/ existing diagnostic tests for enteric diseases along with development of more user friendly and comprehensive point of care tests, enteric vaccine evaluation and efficacy testing, estimation of disease burden based on sero-surveillance etc. .
Title of the project: DOMI project of IVI: Disease
burden study of typhoid fever and cholera in eastern
Kolkata, West Bengal, India.
Funding Agency: BMGF through IVI
Duration: 2002-2004
Role: Co-I
Title of the project: Phase IV effectiveness trial of Vi
vaccine against typhoid
Funding Agency: BMGF through IVI
Duration: 2004-2006
Role: Co-I
Title of the project: Scientific Evaluation of
anti-typhoid claim.
Funding Agency: NIF-DST Task Force
Duration: 2008-2010
Role: PI
Title of the project: Surveillance for Dengue fever in
Eastern Kolkata, West Bengal, India.
Funding Agency: BMGF through PDVI
Duration: 2008-2010
Role: Co-I
Title of the project: In vitro studies on Novel approach
of Vaccination with cocktail of LPS immunogen derived
from common Salmonella Sp.
Funding Agency: ICMR
2013-2014
Role: PI
Title of the project: Studies on the molecular typing S. Typhi isolates of Kolkata its relevance in controlling
the drug-resistant organisms.
Funding Agency: WB DST
Duration: 2014-2017
Role: PI
Title of the project: NICED-Regional Virus Research
Diagnostic Lab
Funding Agency: DHR, GOI
Duration: 2016 - ongoing
Role: PI
Title of the project: A multi-centric study to estimate
the sero-prevalence of dengue virus infection in India
Funding Agency: ICMR, Delhi
Duration: 2017-2018
Role: PI
Title of the project: Preparation of NOSODE from
Escherichia coli and Vibrio cholera: the preclinical
effectiveness and safety evaluation
Funding Agency: Central Council for Research in
Homeopathy (CCRH), Delhi
Duration: 2017-2019
Role: PI
Title of the project: National Surveillance System for
Enteric Fever in India (NSSEFI)
Funding Agency: BMGF through CMC, Vellore, India
2017-2020
Role: PI
Title of the project: Immunogenicity and Safety of Rotavac® and Rotasiil® Administered in an
Interchangeable Dosing Schedule among Healthy Indian
Infants: A Multicentric, Phase IV, Open-Labelled,
Randomized, Controlled Trial (RVICS)
Funding Agency: MoH&FW, GoI through ICMR
Duration: 2018-2020
Role: PI
Title of the project: Evaluation of a Typhoid Conjugate
Vaccine Introduction Program - Navi Mumbai Municipal
Corporation, India
Funding Agency: WHO, India
Duration: 2018-2020
Role: PI
Title of the project: Sanipath Typhoid - Assessment of
Typhoid Exposure Pathways In Low-Income Urban Settings
Funding Agency: Emory University
Duration: 2018-2021
Role: PI
Title of the project: Etiology of Childhood Pneumonia in
India: An ICMR Task Force Study
Funding Agency: ICMR, Delhi
Duration: 2018-2020
Role: Coordinator
Title of the project: Human pulmonary paragonimiasis in
crab eating communities and smear negative suspected TB
cases from some states of India
Funding Agency: ICMR, Delhi
Duration: 2019-2021
Role: PI
Title of the project: Strengthening Laboratory
Surveillance for Pneumococcal Meningitis in India to
Understand the Impact of Pneumococcal Conjugate Vaccine
(PCV) rollout
Funding Agency: ICMR, Delhi
Duration: 2019-2022
Role: PI
Title of the project: National Repository of
Antimicrobial Resistant Bacterial Isolates (NRAMRB) at
ICMR-NICED: A Pilot study
Funding Agency: ICMR-Delhi
Duration: 2019-2020
Role: PI
Title of the project: Rational use of drugs
Funding Agency: ICMR-Delhi
Duration: 2019-2022
Role: PI
Title of the project: Centre for Product Development and
Rational Use of Drugs
Funding Agency: ICMR-Delhi
Duration: 2019-2024
Role: PI
Title of the project: Mobile application for
immunization data in India (MAIDI)
Funding Agency: ICMR-NICED
Duration: Feb 2020 for 9 months
Role: PI
Title of the project: Estimation of V. cholerae O1
infection in India: a step towards identification of
cholera hotspots
Funding Agency: ICMR-Delhi
Duration: Aug. 2020 for 4 months
Role: PI
Title of the project: Establishment of ten ICMR-Biorepositories for COVID-19
Funding Agency: ICMR-Delhi
Duration: Sept. 2020 for 6 months
Role: PI
Title of the project: An Event-driven, Phase 3,
Randomized, Double-blind, Placebo-controlled,
Multicenter study to evaluate the efficacy, safety,
immunogenicity and Lot-to-Lot consistency of BBV 152, a
Whole-virion inactivated SARS-CoV-2 vaccine in adults
≥18 years of age
Funding Agency: ICMR-Delhi
Duration: December 2020
Role: CoI
Title of the project: Impact of improved diagnostic
tools practices training and communication on acute
fever case management and antibiotic prescriptions for
children, and adolescents presenting at outpatient
facilities in the community clinics of ICMR-NICED, India
Funding Agency: ICMR-Delhi and FIND
Duration: March 2021 for 18 months
Role: PI
Title of the project: National Repository of
Antimicrobial Resistant Bacterial (NRAMRB): a facility
under the "AMR Hub" for addressing AMR research across
India
Funding Agency: ICMR-Delhi
Duration: August 2021 for 3 yrs.
Role: PI
Title of the project: Priorities for the environmental
dimension of Antimicrobial Resistance (AMR) in India
Funding Agency: UNEP
Duration: July 2021 for 6 months
Role: PI
Title of the project: A Prospective, Multicentre,
Randomized, Active-controlled, Observer-blind, Phase II
study seamlessly followed by a Phase III study to
evaluate the Safety, Tolerability and Immunogenicity of
the candidate HGCO19 (COVID-19 vaccine) in healthy
subjects.
Funding Agency: Gennova Biopharmaceuticals Ltd.
Duration: December 2021 for14 months
Role: PI
Hospital based Surveillance system for Diarrhoeal
Diseases
Studies on mechanism of antimicrobial resistance especially
fluoroquinolone resistance among Salmonella Typhi Kolkata
isolates
Studies on evolution of flouroquinolone and azithromycin
resistance in Salmonella Typhi blood isolates
Studies on antimicrobial resistance & molecular subtypes of
Gram Negative bacilli isolated from hospitalized sepsis
patients.
No. of Publications - 241; Book Chapters - 8; Book Review - 1