ICMR-National Institute of Cholera and Enteric Diseases
सी एम आर - राष्ट्रीय कॉलरा और आंत्र रोग संस्थान
Department of Health Research, Ministry of Health and Family Welfare, Government of India
स्वास्थ्य अनुसंधान विभाग, स्वास्थ्य और परिवार कल्याण मंत्रालय, भारत सरकार
WHO Collaborating Centre For Research and Training On Diarrhoeal Diseases
Dr. Mamta Chawla-Sarkar joined as Scientist C in Division. of Virology, NICED, Kolkata in January 2006. Dr Chawla Sarkar gained her Master's in Zoology in 1992 from Calcutta University and acquired the degree of Ph.D from Bose Institute-Jadavpur University, Kolkata in 1999. She did her Post-doctoral research work as Research Associate for six years in the Center for drug discovery & development, Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland. The research project was on analysis of the genes involved in antitumor effects of Interferons and the mechanisms underlying IFN resistance in tumors of different histopathologies. In addition she was also involved in project on role of heme insertion in dimerization and activity of inducible nitric oxide synthetase and study the effect of heme binding inhibitors in modulating NOS activity in various pathological disorders.
After joining Division of Virology at NICED, Dr Chawla-Sarkar has been involved in studying two viruses namely Influenza virus and Rotavirus. Her research focus involves strain surveillance, Host-virus interaction and identifying cellular proteins involved in viral pathogenesis for developing potential antiviral targets. As a scientist -in-charge for Influenza surveillance in NICED, Dr Chawla-Sarkar was responsible for providing laboratory support for states in Eastern India during A/H1N1 pandemic in 2009. In 2010, she was promoted to Scientist D (Assistant Director). In 2013, she was elected Fellow of the National academy of science in India (NASI). She was honored with
"National Women Bioscientist Award" by Department of Biotechnology in 2013.
She is currently working on four projects:
Multisite monitoring of Influenza Virus strains in India.
Analysis of the Rotavirus-host cell interaction: Study of role of Rotavirus encoded proteins and host cellular proteins during virus infection.
Analysis of the Rotavirus-host cell interaction: Study of role of Rotavirus encoded proteins and host cellular proteins during virus infection.
National Rotavirus Surveillance Network.
Dr. Chawla-Sarkar has trained number of students and project staff in various aspects of virus research. Six students have completed their Ph.D. program under her guidance and are now doing post doctoral training in USA and Europe. Currently six students are enrolled for Ph.D. under her guidance. She is the author of more than 65 research papers in the peer-reviewed international journals and two Book chapters in the area of Molecular biotechnology, Immunology, Biological Chemistry and Virology.
Sarkar R, Nandi S, Lo M, Gope A, Chawla-Sarkar M.
Viperin, an IFN-Stimulated Protein, Delays Rotavirus Release by
Inhibiting Non-Structural Protein 4 (NSP4)-Induced Intrinsic
Apoptosis. Viruses. 2021; 13 (7):1324.
Malbari K, Saha P, Chawla-Sarkar M, Dutta S, Rai S,
Joshi M, Kanyalkar M, In quest of small-molecules as potent
non-competitive inhibitors against influenza,Bioorg Chem.2021
Patra U, Mukhopadhyay U, Mukherjee A, Dutta S, Chawla-Sarkar
M. Treading a HOSTile path: Mapping the dynamic landscape of
host cell-rotavirus interactions to explore novel host-directed
curative dimensions. Virulence. 2021; 12(1):1022-1062.
Mukhopadhyay U, Banerjee A, Chawla-Sarkar M, Mukherjee A.
Rotavirus Induces Epithelial-Mesenchymal Transition Markers by
Transcriptional Suppression of miRNA-29b. Front Microbiol. 2021
Sarkar R, Mitra S, Chandra P, Saha P, Banerjee A, Dutta S,
Chawla-Sarkar M. Comprehensive analysis of genomic diversity of
SARS-CoV-2 in different geographic regions of India: An
endeavour to classify Indian SARS-CoV-2 strains on the basis of
co-existing mutations. Arch Virol. 2021; 166(3):801-812.
Banerjee A, Sarkar R, Mitra S, Lo M, Dutta S, Chawla-Sarkar M.
The novel coronavirus enigma: Phylogeny and analyses of
coevolving mutations among the sars-cov-2 viruses circulating in
India. JMIR Bioinformatics and Biotechnology. 2020;1(1):e20735.
C.P. Girish Kumar, Giri S , Chawla-Sarkar M , Gopalkrishna V ,
Chitambar S D , Ray P, Venkatasubramanian S, Borkakoty B, Roy S
, Bhat J , Dwibedi B , Paluru V , Das P , Arora R , Kang G ,
Mehendale S. M. , and National Rotavirus Surveillance Network
investigators. Epidemiology of rotavirus diarrhea among children
less than 5 years hospitalized with acute gastroenteritis prior
to rotavirus vaccine introduction in India. Vaccine. 2020
Giri S, Girish Kumar CP, Khakha SA, Chawla-Sarkar M, Gopalkrishna V, Chitamber SD, Ray P, Venkatsubramaniam S,
Borkakoty B, Roy S, Bhatt J, Dwibedi
7. Maitra A, Chawla Sarkar M, Raheja H , Biswas N. K.,
Singh A., Chakraborti S., Ghosh S., Sarkar S, Patra S, Mondal R.
K, Ghosh T., Chatterjee A., Banu H, Majumdar A, Chinnaswamy S,
Srinivasan N, Dutta S, S Das. Mutations in SARS-CoV-2 Viral RNA
Identified in Eastern India: Possible Implications for the
Ongoing Outbreak in India and Impact on Viral Structure and Host
Susceptibility. Journal of Biosciences 2020; 45: 76.
Das P, Palaru V, Ramani S, Babji S, Arora R, Mehendale SM, Gupte
MD, Kang G. Diversity of rotavirus genotypes circulating in
children < 5 years of age hospitalized for acute gastroenteritis
in India from 2005 to 2016: analysis of temporal and regional
genotype variation. BMC Infect Dis.;2020 Oct 9;20(1):740.
Mitra S, Nayak MK, Majumdar A, Sinha A, Chatterjee S, Deb A,
Chawla-Sarkar M, Dutta S. Development and evaluation of a
multiplex conventional reverse-transcription polymerase chain
reaction assay for detection of common viral pathogens causing
acute gastroenteritis. Diagn Micr Infect Dis. 2020 Aug;
Sarkar R, Patra U, Lo M, Mukherjee A, Biswas A, Chawla-Sarkar
M. Rotavirus activates a noncanonical ATM-Chk2 branch of DNA
damage response during infection to positively regulate
viroplasm dynamics. Cell Microbiol. 2020 Mar; 22(3):e13149 .
Nayak MK, Banerjee A, Sarkar R, Mitra S, Dutta K, Ganguly N,
Ghosh C, Girish Kumar CP, Niyogi P, Panda S, Dutta S,
Chawla-Sarkar M. Genetic characterization of group-A
rotaviruses among children in eastern India during 2014-2016:
Phylodynamics of co-circulating genotypes. Vaccine. 2019 Oct
Mukhopadhyay U, Chanda S, Patra U, Mukherjee A, Komoto S,
Chawla-Sarkar M. Biphasic regulation of RNA interference
during rotavirus infection by modulation of Argonaute2. Cell
Microbiol. 2019 Dec;21(12):e13101.
Mukhopadhyay U, Chanda S, Patra U, Mukherjee A, Rana S,
Mukherjee A, Chawla-Sarkar M. Synchronized Orchestration
of miR-99b and let-7g Positively Regulates Rotavirus Infection
by Modulating Autophagy.Sci Rep. 2019 Feb 4;9(1):1318.
Patra U, Mukhopadhyay U, Sarkar R, Mukherjee A, Chawla-Sarkar
M. RA-839, a selective agonist of Nrf2/ARE pathway, exerts
potent anti-rotaviral efficacy in vitro.Antiviral Res. 2019
Rana S, Datta R, Chaudhuri RD, Chatterjee E, Chawla-Sarkar M,
Sarkar S. Nanotized PPARα Overexpression Targeted to
Hypertrophied Myocardium Improves Cardiac Function by
Attenuating the p53-GSK3β-Mediated Mitochondrial Death
Pathway.Antioxid Redox Signal. 2019 Feb 10;30(5):713-732.
Mukherjee A, Patra U, Bhowmick R, Chawla-Sarkar M.
Rotaviral nonstructural protein 4 triggers dynamin-related
protein 1-dependent mitochondrial fragmentation during
infection. Cell Microbiol. 2018 Jun;20(6):e12831..
Nayak MK,De P, Manna B, Dutta S, Bhadra UK, Chawla-Sarkar M.
Species A rotaviruses isolated from hospitalized patients over 5
years of age in Kolkata, India, in 2012/13.Arch Virol. 2018
Banerjee A, Lo M, Indwar P, Deb AK, Das S, Manna B, Dutta S,
Bhadra UK, Bhattacharya M, Okamoto K, Chawla-Sarkar M.
Upsurge and spread of G3 rotaviruses in Eastern India
(2014-2016): Full genome analyses reveals heterogeneity within
Wa-like genomic constellation. Infect Genet Evol. 2018
Doan YH, Suzuki Y, Fujii Y, Haga K, Fujimoto A, Takai-Todaka R,
Someya Y, Nayak MK, Mukherjee A, Imamura D, Shinoda S,
Chawla-Sarkar M, Katayama K. Complex reassortment events of
unusual G9P rotavirus strains in India between 2011 and
2013.Infect Genet Evol. 2017 Jul 25;54:417-428. .
Chattopadhyay S, Mukherjee A, Patra U, Bhowmick R, Basak T,
Sengupta S, Chawla-Sarkar M. Tyrosine phosphorylation
modulates mitochondrial chaperonin Hsp60 and delays rotavirus
NSP4-mediated apoptotic signaling in host cells. Cell Microbiol.
2017 Mar;19(3). doi: 10.1111/cmi.12670.
Banerjee A, De P, Manna B, Chawla-Sarkar M. Molecular
characterization of enteric adenovirus genotypes 40 and 41
identified in children with acute gastroenteritis in Kolkata,
India during 2013-2014. J Med Virol. 2017Sep 19; 89:606-614.
Datta R, Bansal T, Rana S, Datta K, Datta Chaudhuri R,
Chawla-Sarkar M, Sarkar S. Myocyte-Derived Hsp90 Modulates
Collagen Upregulation via Biphasic Activation of STAT-3 in
Fibroblasts during Cardiac Hypertrophy.Mol Cell Biol. 2017 Mar
Mukherjee A, Nayak MK, Dutta S, Panda S, Satpathi BR,
Chawla-Sarkar M. Genetic Characterization of Circulating
2015 A(H1N1)pdm09 Influenza Viruses from Eastern India. PLoS
One. 2016 Dec 20;11:e0168464.
Mandal P, Mullick S, Nayak MK, Mukherjee A, Ganguly N, Niyogi P,
Panda S, Chawla-Sarkar M. Complete genotyping of unusual
species A rotavirus G12P and G10P isolates and evidence
of frequent in vivo reassortment among the rotaviruses detected
in children with diarrhea in Kolkata, India, during 2014. Arch
Virol. 2016 Jul 22;161:2773-2785.
Chanda S, Nandi S, Chawla-Sarkar M. 2016. Rotavirus induced miR-142-5p elicits proviral milieu by targeting Non-canonical
TGFβ signalling and apoptosis in cells. Cell Microbiol. 18(5):733-47 2015.
Deb Chanda S, Banerjee A, Chakrabarti S. and Chawla Sarkar M.
Cordecypin an Adenosine Analogue executes anti-RV effects by
stimulating Induction of Type I Interferon. J Virol Antiviral
Res. 2015 May 25;4:2.
Shaheen M, M. Borysanyiova, M. Chawla Sarkar, N. EL-Esnawy.
2015. In vitro effect of Dodonaea viscose extracts on the replication of coxackivirus B3 and rotavirus.
J Microbiol Antimicrob Agents 1(2): 47-50.
Datta R, T. Bansal, S. Rana, K. Datta, S. Chattopadhyay, M. Chawla-Sarkar, S. Sarkar. 2015.Hsp90/Cdc37 assembly modulates TGFβ receptor-II to act as a profibrotic regulator of TGFβ signaling during cardiac hypertrophy. Cell Signal. 27(12):2410-24.
Sarkar T, S Das , A De , P Nandy, S Chattopadhyay , M. Chawla-Sarkar, A Nandy.
H7N9 influenza outbreak in China 2013: In silico analyses of conserved segments of the
hemagglutinin as a basis for the selection of peptide vaccine targets. Comput Biol Chem.59 Pt A:8-15.
Bhowmick R, A. Mukherjee, U. Patra , M.Chawla-Sarkar. 2015. Rotavirus disrupts cytoplasmic P bodies during infection.
Virus Res. 210:344-54.
Chadha M.S, V.A Potdar, S. Saha, P..A. Koul, S. Broor, L.
Dar, M. Chawla-Sarkar, D. Biswas, P. Gunasekaran, A. M. Abraham,
S. Shrikhande, A.,Jain, B. Anukumar, R.B. Lal, A.C. Mishra. 2015.Dynamics
of influenza seasonality at sub-regional levels in India and
implications for vaccination timing.PLoS One. 10(5):e0124122.
Rana S., K. Datta, T.L. Reddy, E. Chatterjee, P. Sen, M.
Pal-Bhadra, U. Bhadra, A. Pramanik, P. Pramanik, M. Chawla-Sarkar,
S. Sarkar. 2015. A spatio-temporal cardiomyocyte targeted vector
system for efficient delivery of therapeutic payloads to regress cardiac
hypertrophy abating bystander effect. J Control Release.
Mullick S., A. Mukherjee , S. Ghosh , G.P. Pazhani, D. Sur , B. Manna , J. P. Nataro,M.M Levine , T. Ramamurthy , M.Chawla-Sarkar.2014
.Community based case-control study of rotavirus gastroenteritis among young children during 2008-2010 reveals vast genetic diversity and increased prevalence
of G9 strains in Kolkata. PLoS One.9 (11):e112970.
Potdar V.A., M. R. Dakhave, P.B. Kulkarni, S.A. Tikhe, S. Broor, P. Gunashekaran, M. Chawla-Sarkar, A.Abraham,
D. Biswas, K.N. Patil, A.A. Kadam, S.S. Kode, A.C. Mishra, M.S. Chadha. 2014. Antiviral drug profile of human influenza A B
viruses circulating in India: 2004-2011. Indian J Med Res. 140(2):244-51.
Mullick S, P. Mandal, M.K. Nayak, S. Ghosh, P. De, K. Rajendran, M.K. Bhattacharya, U. Mitra, T. Ramamurthy, N. Kobayashi,
M. Chawla-Sarkar. 2014. Hospital based surveillance and genetic characterization of rotavirus
strains in children (5 years) with acute gastroenteritis in Kolkata, India, revealed resurgence of G9 and G2 genotypes during 2011-2013.
Vaccine 32 Suppl 1:A20-28.
Bhowmick R, G. Banik, S. Chanda, S. Chattopadhyay, M.Chawla-Sarkar. 2014. Rotavirus infection induces G1 to S phase
transition in MA104 cells via Ca+ 2;/Calmodulin pathway. Virology 454-455:270-279.
Nandi S, S. Chanda, P. Bagchi, M. K. Nayak., R. Bhowmick, M.Chawla-Sarkar 2014. MAVS
protein is attenuated by rotavirus nonstructural protein 1. PLoS One. 18;9(3):e92126.
Panda S, A.K. Deb, M. Chawla-Sarkar, T. Ramamurthy, S. Ganguly, P. Pradhan, A. Chakraborty,
S. Desai, M.D. Gupte, R.Dhere 2014. Factors associated with diarrhoea in young children and
incidence of symptomatic rotavirus infection in rural West Bengal, India. Epidemiol Infect. 142:1848-1858.
Nayak MK, A.S Agrawal, S. Bose, S. Naskar, R.
Bhowmick, S. Chakrabarti, S. Sarkar, M. Chawla-Sarkar. 2014.
Antiviral activity of baicalin against influenza virus H1N1-pdm09 is due
to modulation of NS1-mediated cellular innate immune responses. J
Antimicrob Chemother. 69:1298-1310.
Bagchi P, R Bhowmick, S Nandi, M Kant Nayak, M.
Chawla-Sarkar.2013. Rotavirus NSP1 inhibits interferon induced
non-canonical NF?B activation by interacting with TNF receptor
associated factor 2. Virology 444: 41- 44
Roy Mukherjee T, S Chanda, S Mullick, P De, M Dey-Sarkar,
M.Chawla-Sarkar 2013. Spectrum of respiratory viruses circulating in
eastern India: prospective surveillance among patients with
influenza-like illness during 2010-2011. J Med Virol. 85: 1459-1465.
Mazumdar J, M Chawla-Sarkar, K Rajendran, A Ganguly, UK
Sarkar, S,Ghosh, MD Sarkar, S. Maulik. Burden of respiratory tract
infections among paediatric in and out-patient units during 2010-11. Eur
Rev Med Pharmacol Sci. 17: 802-808.
Bhowmick R., U.C. Halder, S. Chattopadhyay, M.K. Nayak,
M. Chawla-Sarkar. 2013. Rotavirus-Encoded Nonstructural Protein 1
Modulates Cellular Apoptotic Machinery by Targeting Tumor Suppressor
Protein p53. J Virol. 87(12):6840-50.
Roy Mukherjee T., A. Mukherjee, S. Mullick, M.
Chawla-Sarkar. 2013. Full genome analysis and
characterization of influenza C virus identified in Eastern India.
InfectGenet Evol. 16:419-25.
Chattopadhyay S, T. Basak, M.K. Nayak, G. Bhardwaj, A.
Mukherjee, R. Bhowmick, S. Sengupta, O. Chakrabarti, N.S. Chatterjee,
M. Chawla-Sarkar.2013. Identification of Cellular Calcium
Binding Protein Calmodulin as a Regulator of Rotavirus A Infection
during Comparative Proteomic Study. PLoS One. 8(2):e56655.
Mukherjee A, S. Mullick, A.K. Deb, S. Panda, M.
Chawla-Sarkar. 2013. First report of human rotavirus G8P
gastroenteritis in India: evidence of ruminants-to-human zoonotic
transmission. J. Med. Virol. 85(3):537-45.
Bagchi P, S. Nandi, M.K Nayak, M. Chawla-Sarkar. 2013.
Molecular Mechanism behind Rotavirus NSP1-Mediated PI3 Kinase
Activation: Interaction between NSP1 and the p85 Subunit of PI3 Kinase.
J Virol. 87(4):2358-2362.
Ghosh S, N. Urushibara, M. Chawla-Sarkar, T.
Krishnan, N. Kobayashi. 2013. Whole genomic analyses of
asymptomatic human G1P, G2P and G3P rotavirus strains reveal
intergenogroup reassortment events and genome segments of artiodactyl
origin. Infect Genet. Evol.. 16C: 165-173.
Mullick S, A. Mukherjee, S. Ghosh, G.P. Pazhani, D. Sur,
B. Manna, J.P. Nataro, M.M. Levine, T. Ramamurthy, M. Chawla-Sarkar.
2013. Genomic analysis of human rotavirus strains G6P and
G11P isolated from Kolkata in 2009 reveals interspecies transmission
and complex reassortment events. Infect. Genet. Evol. 14:15-21.
Roy Mukherjee T, A.S. Agrawal, S. Chakrabarti, M. Chawla-Sarkar. 2012. Full genomic analysis of an influenza A (H1N2) virus identified during
2009 pandemic in Eastern India: evidence of reassortment event between co-circulating A(H1N1)pdm09 and A/Brisbane/10/2007-like H3N2 strains.
Virol J. 9: 233.
Mukherjee A, S. Mullick, N. Kobayashi, M. Chawla-Sarkar. 2012. The first identification of rare human group A
rotavirus strain G3P with severe infantile diarrhea in eastern India. Infect Genet Evol. 12: 1933-1937.
Bagchi P, S Nandi, S Chattopadhyay, R Bhowmick, UC Halder, MK Nayak, N Kobayashi, MChawla-Sarkar.2012.
Identification of common human host genes involved in pathogenesis of different rotavirus strains: an attempt to recognize probable
antiviral targets.Virus Res. 169: 144-153.
Ghosh A, S. Chattopadhyay, M. Chawla-Sarkar, P. Nandy, A. Nandy. 2012. In silico
study of rotavirus VP7 surface accessible conserved regions for antiviral drug/vaccine design. PLoS One.7: e40749
Kahn G., S. Fitzwater, J. Tate, G. Kang, N. Ganguly, G. Nair, D. Steele, R. Arora,
M. Chawla-Sarkar, U. Parashar, M. Santosham. 2012. Epidemiology and Prospects for
Prevention of Rotavirus Disease in India. Indian Pediatr. 49: 467- 474.
Sarkar M., S. Chanda, S. Chakrabarti, J. Mazumdar, A. Ganguly, M.S.Chadha, A.C. Mishra, M. Chawla-Sarkar. 2012.
Surveillance in Eastern India (2007-2009) revealed reassortment event involving NS and PB1-F2 gene segments among co-circulating
influenza A subtypes. Virol J. 9: 3.
Mukherjee A., M.K. Nayak, T. Roy, S. Ghosh, T.N. Naik, N. Kobayashi, M. Chawla-Sarkar 2012. Detection of
human G10 rotavirus strains with similarity to bovine and bovine-like equine strains from untypable samples. Infect Genet Evol. 12: 467- 470.
Chadha M.S., S. Broor, P. Gunasekaran, V.A. Potdar, A. Krishnan, M Chawla-Sarkar,
D. Biswas, A.M. Abraham, S.V Jalgaonkar, H.,Kaur, A. Klimov, R.B Lal, A Moen, L. Kant,
A.C Mishra. 2012. Multisite virological influenza surveillance in India: 2004-2008. Influenza Other Respi Viruses. 6: 196-203.
Halder U.C, P. Bagchi, S.Chattopadhyay, D. Dutta, M. Chawla-Sarkar. 2011. Cell death regulation during
influenza A virus infection by matrix (M1) protein: a model of
viral control over the cellular survival pathway. Cell Death Dis. 2: e197.
Roy T., A.S Agrawal, A. Mukherjee, A.C Mishra, M.S. Chadha, H. Kaur, M.Chawla-Sarkar.2011.Surveillance and molecular
characterization of human influenza B viruses during 2006-2010 revealed co-circulation of Yamagata-like and Victoria-like strains in
eastern India. Infect Genet Evol. 11:1595- 1601.
Koul P.A., M.A. Mir, N.K. Bali, M. Chawla-Sarkar, M. Sarkar, S. Kaushik, U.H. Khan, F Ahmad, R, Garten, R,B, Lal, S. Broor.
2011. Pandemic and seasonal influenza viruses among patients with acute respiratory illness in Kashmir (India).
Influenza Other Respi Viruses. 5: e521-527.
Mukherjee A and
Chawla-Sarkar M. Rotavirus Infection: A Perspective on Epidemiology,
Genomic Diversity and Vaccine Strategies. 2011. Review, Indian J
Virol, 22: 11-23.
Ghosh A, Chawla-Sarkar
M, Stuehr DJ. 2011 Hsp90 interacts with inducible NO synthase
client protein in its heme-free state and then drives heme insertion by
an ATP-dependent process. FASEB J. 25: 2049-2060.
Mukherjee A, Ghosh S,
Bagchi P, Dutta D, Chattopadhyay S, Kobayashi N, Chawla-Sarkar M.
Full genomic analyses of human G4P, G4P,G9P and G10P
strains from North-eastern India: Evidence for interspecies transmission
and complex reassortment events. 2011 Clin Microbiol Infect,
Sarkar M, A. S. Agrawal,
R. Sharma Dey, S. Chattopadhyay, R. Mullick, P. De, S. Chakrabarti,
M. Chawla-Sarkar. 2011. Molecular characterization and comparative
analysis of pandemic H1N1/2009 strains with co-circulating seasonal
H1N1/2009 strains from eastern India. Arch Virol. 156: 207-217.
Agrawal A. S, T. Roy,
S. Ghosh, M. Chawla-Sarkar. 2011. Genetic variability of attachment
(G) and Fusion (F) protein genes of human metapneumovirus strains
circulating during 2006-2009 in Kolkata, Eastern India. Virol J. 8:
Dey R. S, S. Ghosh, M.
Chawla-Sarkar, S. Panchalingam, J. P. Nataro, D. Sur, B. Manna, T.
Ramamurthy. 2011. Circulation of a novel pattern of infections by
enteric adenovirus serotype 41 among children below 5 years of age in
Kolkata, India. J Clin Microbiol. 49: 500-505.
Yamamoto D, S. Ghosh, M.
Kuzuya, Y.H. Wang, X. Zhou, M. Chawla-Sarkar, S.K. Paul, M.
Ishino, N. Kobayashi. 2011. Whole-genome characterization of
human group C rotaviruses: identification of two lineages in the VP3
gene. J Gen Virol. 92:361-369.
Mukherjee A, Roy T,
Agrawal AS, Sarkar M, Dey R, Chakrabarti S, Chawla-Sarkar M.2010 Prevalence and epidemiology of pandemic H1N1strains in
hospitals of Eastern India. J Pub Health Epidemiol, 2: 171-174.
Agrawal, A. S., M.
Sarkar, S. Ghosh, T. Roy, S. Chakrabarti, R. Lal, A. C. Mishra, M. S.
Chadha, M. Chawla-Sarkar. 2010. Genetic characterization of
circulating seasonal Influenza A viruses (2005-2009) revealed
introduction of oseltamivir resistant H1N1 strains during 2009 in
eastern India. Infect Genet Evol. 10: 1188-1198.
Chattopadhyay, S., P.
Bagchi, D. Dutta, A. Mukherjee, N. Kobayashi, M. Chawla-Sarkar. 2010.
Computational identification of post-translational modification sites
and functional families reveal possible moonlighting role of rotaviral
proteins. Bioinformation, 4(10): 448-451.
Bagchi P, D. Dutta, S. Chattopadhyay, A. Mukherjee,
U.C. Halder, S. Sarkar, N. Kobayashi, S. Komoto, K. Taniguchi, M.
Chawla-Sarkar 2010. Rotavirus Non-Structural Protein-1 suppresses
virus induced cellular apoptosis to facilitate viral growth by
activating the cell-survival pathways during early stages of infection.
Nagashima S, N. Kobayashi , S.K. Paul , S. Ghosh,
M. Chawla-Sarkar, M.A Hossain, Krishnan T 2010. Identification of
Pb subtype in OP354 like human rotavirus strains by a modified RT-PCR.
Jpn J Infect Dis. 63:208-211.
Ghosh S, N. Kobayashi, S. Nagashima, M.
Chawla-Sarkar, T. Krishnan, B. Ganesh , T. N. Naik. 2010. Full
genome analysis and possible origin of a porcine G12 rotavirus strain
RU172. Virus Genes.40: 382-388.
Yamamoto D, S. Ghosh, B. Ganesh, T. Krishnan, M
Chawla-Sarkar, M. M Alam, T.S. Aung, N. Kobayashi 2010.
Analysis on Genetic Diversity and Molecular Evolution of Human Group B
Rotaviruses Based on Whole Genome Segments. J Gen Virol.
Mukherjee A, S. Chattopadhyay, P. Bagchi, D. Dutta,
N.B. Singh, R. Arora, U.D. Parashar, J.R. Gentsch, M. Chawla-Sarkar
2010. Surveillance and molecular characterization of rotavirus
strains circulating in Manipur, north-eastern India: increasing
prevalence of emerging G12 strains. Infect Genet Evol. 10:311-20.
Ghosh S., N. Kobayashi, S. Nagashima, M.
Chawla-Sarkar, T. Krishnan, B. Ganesh, T.N. Naik 2010.
Molecular characterization of the VP1, VP2, VP4, VP6, NSP1 and NSP2
genes of bovine grop B rotaviruses: identification of a novel VP4
genotype. Arch Virol.
Agrawal A.S., M. Sarkar, S. Chakrabarti, K.
Rajendran, H. Kaur, A.C. Mishra, M.K.Chatterjee, T.N. Naik, M.S. Chadha,
M Chawla-Sarkar2009. Comparitive evaluation of real time
PCR and conventional RT-PCR during a 2 year surveillance for influenza
and respiratory syncytial virus among children with acute respiratory
infections in Kolkata, India reveals distinct seasonality of infection.
J Med Microbiol. 58:1616-1622.
Chattopadhyay D, M. Chawla- Sarkar, T. Chatterjee, R. Sharma Dey,
P. Bag, S.Chakraborti and M. T. Hassan Khan 2009. Recent
advancements for the evaluation of antiviral activities of natural
products. N. Biotechnol. 25:347-368. Review.
Agrawal, A. S., M. Sarkar, S. Ghosh,
M. Chawla Sarkar, N. Chakraborty, M. Basak, T. N. Naik. 2009.
Prevalence of respiratory syncytial virus group B genotype BA-IV strains
among children with acute respiratory tract infection in Kolkata,
Eastern India. J Clin Virol. 45: 358-61.
Mukherjee, A., D. Dutta, S. Ghosh, P. Bagchi,
S. Chattopadhyay, S. Nagashima, N. Kobayashi, P. Dutta, T. Krishnan, T. N. Naik,
M. Chawla Sarkar. 2009. Full genomic analysis of a
human group A rotavirus G9P strain from Eastern India provides
evidence for porcine-to-human interspecies transmission. Arch Virol.
Samajdar, S., S. Ghosh, D. Dutta, M. Chawla Sarkar,
N .Kobayashi, T. N. Naik. 2008. Human group A
rotavirus P Hun9-like and rare OP354 like strains are circulating
among diarhoeic children in Eastern India. Arch Virol. 153:
Samajdar, S., S. Ghosh, M. Chawla Sarkar, U. Mitra,
P. Dutta, N. Kobayashi, T. N. Naik. 2008. Increase in
prevalence of human group A rotavirus G9 strains as an important VP7
genotype among children in Eastern India. J. Clin. Virol. 43:
Nagashima, S., N. Kobayashi, M. Ishino,
M. M. Alam, M. U. Ahmed, S. K. Paul, B. Ganesh, M. Chawla Sarkar, T. Krishnan, T. N. Naik, Y. H. Wang. 2008. Whole genomic characterization of a
human rotavirus strain B219 belonging to a novel group of the genus
Rotavirus. J. Med. Virol. 80: 2023-2033.
Nayak, M. K., G. Balasubramanian, G. C. Sahoo, R.
Bhattacharya, J. Vinje, N. Kobayashi, M. C. Sarkar, M. K. Bhattacharya,
T. Krishnan. 2008. Detection of a novel intergenogroup recombinant
Norovirus from Kolkata, India. Virology. 377: 117-23.
Alam, M. M., N. Kobayashi, M. Ishino, S.
Nagashima, S. K. Paul, M. Chawla Sarkar, T. Krishnan, T. N. Naik. 2008.
Identical rearrangement of NSP3 genes found in three independently
isolated virus clones derived from mixed infection and multiple passages
of Rotaviruses. Arch. Virol. 153: 555-559.
Panda, K., M. Chawla Sarkar, C. Santos, T.
Koeck, S. C. Erzurum, J. F. Parkinson and D. J. Stuehr. 2005.
Visualizing inducible nitric-oxide synthase in living cells with a heme-binding
fluorescent inhibitor. Proc. Natl. Acad. Sci. U S A. 102:
Vaziri, S. A., J. Hill, K. Chikamuri, M. Chawla Sarkar, and R. Ganapathi. 2005. Sensitization of DNA
damage induced apoptosis by proteosome inhibitor PS-341 is p53 dependent
involves target proteins 14-33 sigma surviving. Mol. Cancer Ther.
Sarkar S, Chawla-Sarkar M, Young D,
Nishiyama K, Rayborn ME, Hollyfield JG, Sen S. Myocardial cell death and
regeneration during progression of cardiac hypertrophy to heart failure.
2004 J Biol Chem. 279: 52630-52642.
Chawla Sarkar, M., S. Bae, F. J. Reu, B. S.
Jacobs, D. J. Lindner and E. C. Borden. 2004. Down-regulation of
Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant
melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death and
Differentiation. 11: 915-923.
Chawla Sarkar, M., J. A. Bauer, J. A. Lupica,
B. Morrison, Z. Tang, R. K. Oates, A. Almasan, J. A. DiDonato, E. C.
Borden and D. J. Lindner. 2003. Suppression of NF-?appa B
survival signaling by nitrosylcobalamin sensitizes neoplasms to the
anti-tumor effects of Apo2L/TRAIL. J. Biol. Chem. 278:
Leaman, D. W., M. Chawla Sarkar, K. Vyas, A.
Ozdemir and E. C. Borden. 2003. Greater potency of IFN-beta
compared to IFN-alpha2 in inducing interferon stimulated genes (ISGs) in
Melanoma. Identification of new ISGs by oligonucleotide microarray. J. IFN. and Cytokine Res. 23: 745-756.
Chawla Sarkar, M., D. Lindner, Y. Liu, B. Williams, G. Sen, R. Silverman and E. C. Borden. 2003. Apoptosis
and Interferons: Role of interferon -stimulated genes as mediators of
apoptosis. (Review) Apoptosis, 8: 237-249.
Chawla Sarkar, M., D. W. Leaman, B. S. Jacobs
and E. C. Borden. 2002. IFN pretreatment sensitizes melanoma
cells to tumor necrosis factor related apoptosis inducing ligand
(TRAIL/Apo2L) induced apoptosis. J. Immunol. 169: 847-855.
Chawla Sarkar. M., D. W. Leaman, B. S. Jacobs,
R. J. Tuthill, M. Chatterjee Kishore, G. Stark and E. C. Borden. 2002.
Resistance to Interferons does not correlate with expression and
activation of signal transducer and activator of transcription (STAT1)
in melanoma cell lines. J. IFN. and Cytokine Res. 22: 603-613.
Basu, A., M. Chawla Sarkar and S. K. DasGupta. 2002. The repA and repB domains of Mycobacterial
plasmid pAL5000 replication region act synergistically to activate the
formation of an origin complex. J. Bacteriol. 184: 2204-2214.
Leaman, D. W., M. Chawla Sarkar, K. Vyas, K.
Tamai and E. C. Borden. 2002. Identification of X-linked
inhibitor of apoptosis associated factor-1 (XAF1) as an IFN-stimulated
proapoptotic gene. J. Biol. Chem. 277: 28504-28511.
Morrison, B. H., J. A. Bauer, J. Hu, R. W.
Grane, A. M. Ozdemir, M. Chawla Sarkar, B. Gong, A. Almasan, D. V.
Kalvakolanu and D. J. Lindner. 2002. Inositol hexakisphohate
kinase 2 sensitizes ovarian carcinoma cells to multiple cancer
therapeutics. Oncogene. 21: 1882-1889.
Chawla Sarkar, M., D. W. Leaman and E. C.
Borden. 2001. Preferential induction of apoptosis by IFN
compared to IFN: Correlation with TRAIL/Apo2L induction in melanoma
cell lines. Clinical Cancer Research. 7: 1821-1831.
Chawla, M., and S. K. DasGupta. 1999.
Transposition induced structural instability of E.coli - mycobacteria
shuttle vectors. Plasmid. 41: 135-140.
Mukherjee A, Chatopadhyay S, Chawla-Sarkar M. Rotavirus
Infection in India: A Major Cause of Childhood Gastroenteritis.
Proc National Acad Sci, India Section B: Biol Sci. 2012 Mar
Kahn G, Fitzwater S, Tate J, Kang G, Ganguly N, Nair G,
Steele D, Arora R, Chawla Sarkar M, Parashar U, Santosham M.
Epidemiology and prospects for prevention of rotavirus disease
in India. Indian Pediatr. 2012 Jun 1;49(6):467-74.
Mukherjee A, Chawla-Sarkar M. Rotavirus infection: a
perspective on epidemiology, genomic diversity and vaccine
strategies. Indian J Virol. 2011 Jun 1;22(1):11-23
Chattopadhyay D, Chawla-Sarkar M, Chatterjee T, Dey RS,
Bag P, Chakraborti S, Khan MT. Recent advancements for the
evaluation of anti-viral activities of natural products. New
Biotechnol 2009 Jun 30;25(5):347-68.
Chawla-Sarkar M, Lindner DJ, Liu YF, Williams BR, Sen GC,
Silverman RH, Borden EC. Apoptosis and interferons: role of
interferon-stimulated genes as mediators of apoptosis. Apoptosis
2003 Jun 1;8(3):237-49.
Kobayashi N, Ishino M, Wang YH, Chawla-Sarkar M, Krishnan
T, Naik TN. Diversity of G-type and P-type of human and animal
rotaviruses and its genetic background. Communicating Curr Res
Educ Top Trends ApplMicrobiol. 2007:847-58..
Chawla-Sarkar M., P. Masci and E C Borden.Interferons for cancer
therapy: Key contributions of recombinant biotechnology,InEd
Rodney, J. Y. Ho and M. Gibaldi (ed.), Biotechnology &
Biopharmaceuticals: Transforming Proteins and Genes into Drugs.
J Wiley & Sons Inc., New Jersey, USA. 2003: p. 161-179.