ICMR - National Institute for Research
in Bacterial Infections

आईसीएमआर - राष्ट्रीय जीवाणु संक्रमण अनुसंधान संस्थान

Department of Health Research, Ministry of Health and Family Welfare, Government of India
स्वास्थ्य अनुसंधान विभाग, स्वास्थ्य और परिवार कल्याण मंत्रालय, भारत सरकार
WHO Collaborating Centre For Research and Training On Diarrhoeal Diseases


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Director's Desk

In 1962, about 54 years ago, "Cholera Research Centre" was established in Calcutta (Kolkata) by Indian Council of Medical Research (ICMR) to conduct research on prevention and control of cholera and other diarrheal diseases.In 1968, the Centre was given the status of "International Reference Centre for Vibrio Phage Typing" by the WHO following the outstanding studies on cholera phages in Kolkata and later on, in 1978, it was designated as the "WHO Collaborative Centre for Reference and Research on Vibrios". Subsequently, ICMR converted this Centre into a full-fledged research organization with the status of a "National Institute" and renamed it as "National Institute of Cholera and Enteric Diseases" (NICED) in 1979. The WHO recognized this Institute as "WHO Collaborative Centre for Research and Training on Diarrhoeal Diseases" in 1980. More

News & Events

  • Five-Day Workshop on Capacity Building in Systematic Review & Meta-Analysis
    Organized by : ICMR - National Institute for Cholera and Enteric Diseases
    in collaboration with World Health Organization
    05 to 09 August 2024
    | 10:00 A.M. - 05:30 P.M.
    View Workshop Brochure

  • Renaming of ICMR Institutes in pursuance of interim recommendations made by the Performance Evaluation Committee.
    No. 16//18/2024-Admn./e- 184719  Dated: 28/05/2024
    In continuation to ICMR Office Memorandum of even number dated 10/04/2024 on
    the subject mentioned above, the ICMR- NICED was transformed and renamed as "National Institute of Bacterial Infections". Now, DG ICMR has decided to incorporate the term "research" and Institute is now renamed as "ICMR-National Institute for Research in Bacterial Infections" (ICMR-NIRBI).
    Henceforth, all future correspondence may be addressed at the new name of the Institute.
    View Notice [PDF]

  • ACSIR Ph.D. Programme
    View Details [PDF]

  • Topic: Foundation Day 2024
    Time: Mar 1, 2024 11:00 AM Mumbai, Kolkata, New Delhi
    View Invitation [PDF]

    Joining Details

    Join Zoom from PC, Mac, iOS or Android: 
    Meeting ID: 842 0801 1176
  • Swachhata Hi Seva
    15 September - 2 October 2023
    Garbage Free India

  • IPV-01 - Vaccine Trial at ICMR-NICED: Request for participationI

    ICMR-NICED, a premier research organisation, under the Dept. of Health Research, Ministry of Health and Family Welfare, Govt. of India, is going to initiate a CDSCO approved regulatory trial entitled "A Phase II/III, Multicenter, Double-Blind, Randomized, Active Controlled Study to evaluate Safety and Immunogenicity of SII Inactivated Salk Polio Vaccine (Adsorbed) in comparison with SII (Serum Institute of India) Licensed Inactivated Poliovirus Vaccine (IPV)". View Details

Impact assessment of administering Oral Cholera Vaccine in selected cholera vulnerable districts of West Bengal.

- An Vaccine implementation Research by ICMR- NICED in collaboration with State Public Health System, Govt of West Bengal.

Cholera remains a global public health problem with developing countries bearing the burnt many folds. WHO - Global Task Force on Cholera Control (GTFCC) has declared to End Cholera by 2030 to which India is also committed as a Nation.

Prevention of Cholera outbreak always remained a challenge in countries like India where there are lots of slum populations with high population density. Achieving cholera control through improving water, hygiene, and sanitation may not be feasible at times and require sustained effort and commitment. In such a situation, the Oral Cholera Vaccine (OCV) is an important intervention to address immediately the cholera outbreak menace.

In this regard, ICMR-NICED Kolkata is taking the initiative through an ICMR-funded project for health system implementation of OCV in selected cholera-vulnerable districts of West Bengal utilizing the state health machinery so that effectiveness, challenges, and future policy decisions on requirements of programmatic introduction of OCV may be monitored from real health system perspective.

Euvichol-Plus is an OCV containing inactivated whole cell (WC) of Vibrio cholerae O1 and O139 as active ingredients. It is very safe and around 65% efficacious as evidenced from earlier Randomized Control Trials. The study vaccine (Euvichol-Plus) has been registered in multiple countries, with WHO prequalification for use in subjects 1 year and above. Euvichol-Plus has been procured from UN agencies at subsidized rate, comprising more than 90% of OCV supply to cholera-endemic countries worldwide.

The primary objective is to evaluate the impact of OCV implementation in cholera-endemic zones of West Bengal in a real time situation through a mass vaccination campaign using the public healthcare delivery system. Other specific research components will also be included, like :

  • Age group of target population: children of 1 year and above from cholera-endemic areas, excluding pregnant/lactating women and seriously ill individuals.
  • Oral cholera vaccine (OCV), Euvichol-Plus, will be administered through urban municipality primary health centres or other booths at selected Urban wards (areas with dense clusters in city study map above) with a dosing schedule of Day 0 and Day 14, targeting a total population of around 50,000.
  • The vaccine, WHO-prequalified in 2017, has demonstrated sufficient safety and immunogenicity.
  • Post-vaccination, diarrhoeal disease surveillance network will be in place to monitor and document diarrheal episodes through.

COVID-19 Status Update ICMR-NIRBI

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Information Regarding Testing of Samples for SARS-CoV-2 in the Emergency Situation
View COVID-19 Guidelines: Information Regarding Testing of Samples for SARS-CoV-2 in the Emergency Situation


NIRBI moved from the rented premises at No. 3 Kyd Street to its own establishment at P-33, C.I.T. Road, Scheme XM, Beliaghata, Kolkata 700010, adjacent to the Infectious Diseases Hospital. The unique feature of this Institute is that it conducts basic research and applied clinical and epidemiological research on diarrhoeal diseases under the same roof. This Institute has its basic science set up with well equipped, modern technological facilities in different disciplines such as bacteriology, virology, parasitology, biochemistry, pathophysiology, molecular biology, electron microscopy, immunology and biochemistry.  Read more...

Our Services


Evaluation of quality and performance of HIV, HBV & HCV diagnostic kits. More

Outbreak Investigations

Assessment of the Post-Flood Public Health Situation in Baramulla District, Kashmir during October, 2014 by NICED Scientists. More

Virus Research and Diagnostic Laboratory

Virus Research and Diagnostic Laboratory (VRDL) ICMR-NICED, is a designated Regional Level (Grade - 1) laboratory under the VRDL network established by Department of Health Research, Ministry of Health & Family Welfare,  More

Referral Services

NABL accredited ICMR-NICED Laboratory provides referral services to different Government Organisation for the diagnosis of following diseases. The laboratory, a state of art facility, is manned by a team of skilled personnel.  More

Other Services

Other Services to Government Agencies and Academic Institutions, on request. More

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The Indian Council of Medical Research (ICMR), New Delhi, the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest medical research bodies in the world.
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The Gastrointestinal Tract Pathogens Repository (GTPR) is the national facility at "National institution of Cholera and Enteric Diseases" (NICED) division of Microbiology sponsored by the Indian Council of Medical Research (ICMR), New Delhi for the maintenance, and supply of enteric pathogens.
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