ICMR-National Institute of Cholera and Enteric Diseases
सी एम आर - राष्ट्रीय कॉलरा और आंत्र रोग संस्थान
Department of Health Research, Ministry of Health and Family Welfare, Government of India
स्वास्थ्य अनुसंधान विभाग, स्वास्थ्य और परिवार कल्याण मंत्रालय, भारत सरकार
WHO Collaborating Centre For Research and Training On Diarrhoeal Diseases
Dr. Sandipan Ganguly is the Senior Research Officer in Division of Parasitology. Previously he was a Post Doctoral Faculty in Saint Louis University School of Medicine for two years. He is a Chemistry Major (1996) and Biochemistry post graduate (1998) from University of Calcutta. Dr. Ganguly has acquired his PhD degree also from University of Calcutta and has joined NICED in 2005.
His publications include many scientific papers in renowned International journals, one cover page photograph and one book chapter. He has attended more than 17 National and 15 International symposiums and workshops and presented papers on various infectious diseases issues.
Dr. Ganguly has been working on various aspects of enteric parasitology with special emphasis on molecular and cellular aspects of pathogenesity in these parasites. His major present focus is on the molecular analyses of rRNA biogenesis, mechanism of its formation and its use as a drug target in Giardiasis. Study the effects of oxidative stress on microaerophilic Giardia at its cellular, genome, proteome and metabolomic level, molecular diagnosis of enteric parasites, molecular epidemiology of Coccisides and other enteric parasites in immunocompromized patients. He has visited Gunma University, Keio University, Tokai University and Okayama University, Japan under JICA training program in 2007 and National Institute of Health, Bethesda, Maryland, USA in 2008.
He is an invited lecturer and paper setter and examiner in several Universities like Departments of Microbiology, Zoology, Environmental sciences, Calcutta University. West Bengal University of Technology. Guide for PhD students from University of Calcutta, Utkal University, Jadavpur University. He is a member of The Indian Science Congress Association, Society for Biological Chemists, India, Indian Society for Parasitology, India and Immunology study group, West Bengal, India.
He has achieved several prestigious awards of National and International repute including the Young Scientist Award (2003) from International Union of Biochemistry and Molecular Biology (IUBMB) and presented his work during 2nd Human Proteomics and 19th International Congress of Biochemistry and Molecular Biology in Montreal, Canada. Dr. Ganguly has been awarded by DST Fast track Young Scientist Award (2005-2006) from Department of Science and Technology, Govt. of India and Sir Sriram Award (2007-2008) from National Academy of Medical Sciences, India. He has also been awarded by the Best Poster Award in 15th National Congress of Parasitology, in 2001 at Jodhpur, India and Best Poster Award in Frontiers in Molecular Biology in 2003 at Kolkata.
Dr. Ganguly is an invited expert to deliver radio talks in All India Radio on topics of public interest in infectious gastrointestinal diseases. He has conducted several training programs and workshops including CDC International workshop on diarrheal parasites (2008) for doctors and researchers. He has attended several training courses in molecular biology, immunology, cell biology, biotechnology and bioinformatics and participated in several investigations on infectious diseases and parasitic diarrhea. He is an invited reviewer of National and International journals like Parasitology International.
Das K, LV Nair, A Ghosal, S K Sardar, S Dutta, S Ganguly.
2019. Genetic characterization reveals evidence for an
association between water contamination and zoonotic
transmission of a Cryptosporidium sp. from dairy cattle
in West Bengal, India. Food Waterborne Parasitol. 17: e00064.
Ganguly S, A Ghosal, R Sarkar, S Karmakar, S Dutta. 2019.
Prevalence mapping of Soil Transmitted Helminths in north
eastern states of India - First report. Int. J Sci. Res. 8(9):
Ghosal A and S Ganguly. 2019. Genetic variation of
Giardia lamblia local isolates from Kolkata, India Glob. J. Res.
Ana.; 8(8): 12-13.
Raj D, P. Chowdhury, R. Sarkar, Y. Saito-Nakano, K. Okamoto, S.
Dutta, T. Nozaki, S. Ganguly. 2018. Pyruvate Protects
Giardia Trophozoites from Cysteine-Ascorbate Deprived Medium
Induced Cytotoxicity. Korean J Parasitol. 56(1):1-9.
Datta SP, K. Jana, A. Mondal, S. Ganguly, S. Sarkar.
2018. Multiple paralogues of α-SNAP in Giardia lamblia exhibit
independent subcellular localization and redistribution during
encystation and stress. Parasit Vectors. 11(1):539.
Ganguly S, A. Malhotra, M. Chowdhuri, A. Ghosal, S.K.
Sardar, et al. (2017). Intractable Seizure in a Case of Primary
Amoebic Meningoencephalitis caused by the Free Living Amoeba
Naegleria Fowleri. Arch Parasitol 1:114.
Ganguly S, S. Barkataki, S. Karmakar, P. Sanga, K.
Boopathi, K. Kanagasabai, P. Kamaraj, P. Chowdhury, R. Sarkar,
D. Raj, L. James, S. Dutta, R. Sehgal, P. Jha, M. Murhekar.
2017. High prevalence of soil-transmitted helminth infections
among primary school children, Uttar Pradesh, India, 2015.
Infect Dis Poverty. 6(1):139.
Das K., P. Chowdhury, T. Nozaki and S. Ganguly. 2016. Genetic characterization of Entamoeba histolytica
reveals a significant association of parasite genotype with disease outcome. J Adv Biotechnol. 6:798-806
Sinha A, A. Ray, S. Ganguly, S. Ghosh Dastidar and S. Sarkar. 2015. Variation in the ribosome
interacting loop of the Sec61α from Giardia lamblia. Biol Direct10:56.
Das K, P. Chowdhury, S. Ganguly. 2015. Internal Transcribed Spacer 1 (ITS1) based sequence
typing reveals phylogenetically distinct Ascaris population.
ComputStructBiotechnol J. 13:478-483
Raj D, P. Saini, T. Nozaki, S. Ganguly. 2015. Involvement of pyruvate on oxidative stress management in the
microaerophilic protozoan parasite Giardia lamblia. Int J Adv Res 3(4): 1148-1166
Das K, S Ganguly. 2014. Evolutionary genomics and
population structure of Entamoebahistolytica. Comp Struc
Biotech J 12: 26-33.
Patil SR, FB Arnold, AL Salvatore, B Briceno, S
Ganguly, JM Colford Jr, PJ Gertler. 2014. The Effect of India's
Total Sanitation Campaign on Defecation Behaviors and Child Health in
Rural Madhya Pradesh: A Cluster Randomized Controlled Trial. PLoS
Mukherjee AK, P Chowdhury, K Rajendran, T Nozaki, and
S Ganguly. 2014. Association between Giardia duodenalis and
Coinfection with Other Diarrhea-Causing Pathogens in India. Biomed
Res Int. 2014;2014:786480.
Panda S, AK Deb, MC Sarkar, T Ramamurthy, S Ganguly,
P Pradhan, A Chakraborty, S Desai, MD Gupte and R. Dhere. 2014.
Factors associated with diarrhoea in young children and incidence of
symptomatic rotavirus infection in rural West Bengal, India.
Das K, AK Mukherjee, P Chowdhury, R Sehgal, MK
Bhattacharya, T Hashimoto, T Nozaki and S Ganguly. 2014.
Multilocus sequence typing system (MLST) reveals a significant
association of Entamoebahistolytica genetic patterns with disease
outcome. Parasitology International 63: 308-314
Raj D, E Ghosh, T Nozaki and S Ganguly. 2014.
Differential Gene Expression in Giardia lamblia under Oxidative
Stress: Significance in Drug Designing and Eukaryotic Evolution. Gene
Karmakar S, AK Mukherjee, and S Ganguly.
Electroporation of snoRNA in Giardia lamblia. 2013. Global
J Bio Agri Health Sci. 2(4):20-21
Ghosh A, S Karmakar, AK Mukherjee, D Raj, K Das, S
Sarkar, T Nozaki, and S Ganguly. 2013. The splicosomal protein
SnRNP F binds to both U3 and U14 class of snoRNA in Giardia lamblia.
Global J Bio Agri Health Sci. 2(3):178-184.
Mukherjee AK, P Chowdhury, K Das, D Raj, S Karmakar and
S Ganguly. 2013. Helminth burden among school going
children of southern Bengal, India: A survey report. Global J Bio
Agri Health Sci. 2(3):189-191
Karmakar S, D Raj and S Ganguly. 2013.
Identification of the N-terminal Glycinearginine Rich (GAR) Domain in
Giardia lambliaFibrillarin and Evidence of its Essentiality for
snoRNA Binding. Int.J. Trop. Dis. Health 3(4): 318-327.
Mukherjee AK, S Karmakar, D Raj and S Ganguly. 2013.
Multi-locus Genotyping Reveals High Occurrence of Mixed Assemblages in
Giardia duodenalis within a Limited Geographical Boundary. British
Microbiology Research Journal, 3(2): 190-197
Khalid IM, KA Talukder, M Aslam, R Haque, S Ganguly,
IJ Azmi, MS Hossain, AK Mukherjee, D Raj, I Ahmed, J Kamal, JR Rubino,
AN Kamal. 2013. Natural contamination of human hands with enteric
parasites in Indian Subcontinent. World J Clin Infect Dis. 3(2):
Li W, V Cama, FO Akinbo, S Ganguly, NM Kiulia,
X Zhang, L Xiao. 2013. Multilocus sequence typing of
Enterocytozoonbieneusi: Lack of geographic segregation and existence of
genetically isolated sub-populations. Infect Genet Evol.
Pativada M, SM Nataraju, B Ganesh, K Rajendran, T
Ramamurthy, S Ganguly, MK Bhattacharya, M Ghosh, N Kobayashi, T
Krishnan. 2012. Emerging trends in the epidemiology of human astrovirus
infection among infants, children and adults hospitalized with acute
watery diarrhea in Kolkata, India. Infection Genetics and Evolution12:
Khan SM, C Debnath, AK
Pramanik, L Xiao, T Nozaki and S Ganguly. 2011. Molecular
evidence for zoonotic transmission of Giardia duodenalis among dairy
farm workers in West Bengal, India. Vet Parasitol. 178: 342-345
Sinha A, S Mandal, S
Banerjee, A Ghosh, S Ganguly, A K Sil and S Sarkar. 2011.
Identification and Characterization of a FYVE Domain from the Early
Diverging Eukaryote Giardia lamblia. Curr Microbiol
Nataraju, S. M., M
Pativada, D Chatterjee, MK Nayak, B Ganesh, MK Bhattacharya, T
Ramamurthy, S Ganguly, DR Saha, K Rajendran, M Ghosh, N
Kobayashi, T Krishnan. 2011. Molecular epidemiology of norovirus
infections in children and adults: sequence analysis of region C
indicates genetic diversity of NVGII strains in Kolkata, India.
Epidemiol Infect. 19: 1-9.
Mukherjee, A. K., K. Das, M. K. Bhattacharya, T. Nozaki, S. Ganguly.
2010. Trend of Entamoeba histolytica infestation in Kolkata.
Gut Pathogens. 2: 12.
Nair G. B., T Ramamurthy., M. K Bhattacharya., T Krishnan., S Ganguly.,
K Rajendran., B Manna., M Ghosh., K Okamoto. and Y. Takeda. 2010.
Emerging trends in etiology of diarrheal pathogens in hospitalized cases
at the Infectious Diseases Hospital, Kolkata, India. GUT Pathogens.
Nataraju, S. M., M Pativada, D Chatterjee, MK Nayak, B Ganesh, MK
Bhattacharya, T Ramamurthy, S Ganguly, DR Saha, K Rajendran, M
Ghosh, N Kobayashi, T Krishnan. 2010. Molecular epidemiology of
norovirus infections in children and adults: sequence analysis of region
C indicates genetic diversity of NVGII strains in Kolkata, India.
Epidemiol Infect. 19: 1-9.
Khan, S. M., C Debnath, AK Pramanik, L Xiao, T Nozaki, S Ganguly.
2010. Molecular characterization and assessment of zoonotic
transmission of Cryptosporidium from dairy cattle in West Bengal,
India. Vet Parasitol. 171: 41-47.
Sarkar, S., R Banerjee, S Chanda, P Das, S Ganguly and S Pal.
2010. Effectiveness of inoculation with isolated Geobacillus strains
in the thermophilic stage of vegetable waste composting. Bioresource
Technology 101: 2892-2895.
C Debnath, AK Pramanik, L Xiao, T Nozaki and S Ganguly. 2010.
Molecular characterization and assessment of zoonotic transmission of
Cryptosporidium from dairy cattle in West Bengal, India. Vet
G. B., T Ramamurthy., M. K Bhattacharya., T Krishnan., S Ganguly., K
Rajendran., B Manna., M Ghosh., K Okamoto. and Y. Takeda. 2010.
Emerging trends in etiology of diarrheal pathogens in hospitalized cases
at the Infectious Diseases Hospital, Kolkata, India. GUT Pathog. 2:4
S, R Banerjee, S Chanda, P Das, S Ganguly and S. Pal. 2010.
Effectiveness of inoculation with isolated Geobacillus strains in the
thermophilic stage of vegetable waste composting. Bioresour
Mukherjee A. K., M. K Bhattacharya.,. M Ghosh., K
Rajendran.., and S. Ganguly. 2009. Hospital based
surveillance study on the prevalence of Giardia lamblia,
Cryptosporidium sp. and Entamoeba histolytica in Kolkata.
BMC Research Notes, 2: 110.
Ghosal A., R Bhowmik., R Banerjee., S Ganguly.,
S Yamasaki., T Ramamurthy., T Hamabata and N. S. Chatterjee. 2009.
Characterization and the studies of cellular interaction of native
colonization factor CS6 purified from a clinical isolate of
enterotoxigenic Escherichia coli. Infect Immun 77: 2125-
Ghosh, E., A. Ghosh, A. N. Ghosh, T. Nozaki and
S. Ganguly. 2009. Oxidative stress induced cell cycle blockage and
a protease-independent programmed cell death in microaerophilic Giardia
lamblia. Drug Design, Development and Therapy.3: 1-8.
Ghosh, A., E. Ghosh and S. Ganguly. 2008
Fibrillarin and rRNA processing in enteric parasite Giardia lamblia. Ind
J. of Trop Para.2: 66-74.
Bhowmick, R., A. Ghosal, B. Das, H. Koley,
D. R. Saha, S. Ganguly, R. K. Nandy, R. K. Bhadra, N. S. Chatterjee. 2008. Intestinal adherence
of Vibrio cholerae involves a coordinated interaction between
colonization GbpA and mucin. Infection & Immunity. 76: 4968-77.
Dey, R., N. Majumder, S. Bhattacharjee, S. B. Majumdar, R.
Banerjee, S. Ganguly, P. Das and S. Majumdar. 2007. Leishmania
donovani Induced Ceramide As The Key Mediator of Akt Dephosphorylation
In Murine Macrophages: Role of PKC (zeta) And Phosphatase. Infect. Immun.
Das, P., S. Saha Roy, K. Mitra Dhar, P. Dutta, M. K.
Bhattacharya, A. Sen, S. Ganguly, S. K. Bhattacharya, A. A. Lal and X.
Lihua. 2006. Molecular Characterization of Cryptosporidium
spp. in children in Kolkata, India. J. Clin. Microbiol.44:
Ganguly, S., S. Ghosh, D. Chattopadhyay and P. Das.
2004. Antisense molecular beacon strategy for in situ visualization
of snRNA and fibrillarin protein interaction in Giardia lamblia.
RNA Biology. 1: 48-53.
Ganguly, S., S. Ghosh, D. Chattopadhyay and P. Das.
2003. Localization of fibrillarin and its role in formation of
ribonucleoprotein particles with small nuclear RNAs for
post-transcriptional modification of rRNA in Giardia lamblia.
Mol. Cell. proteomics. 2: 633.
Dasgupta, B., K. Roychoudhury, S. Ganguly, P. K. Sinha,
S. Vimal, P. Das and S. Roy. 2003. Antileishmanial drugs cause
up-regulation of interferon-gamma receptor 1, not only in the monocytes
of visceral leishmaniasis cases but also in cultured THP1 cells. Annals
of Trop. Med. Parasitol.97: 245-257.
Sen, P., S. Mukherjee, G. Bhaumik, P. Das,
N. Choudhury and S. Raha. 2003. Enhancement of catalase activity by
repeatitive low grade H2O2 exposure protects fibroblasts from subsequent
stress-induced apoptosis. Mut. Res. 529: 87-94.
Dasgupta, B., K. Roychoudhury, S. Ganguly, A. Akbar, P.
Das and S. Roy. 2003. Infection of human mononuclear phagocytes
and macrophage-like thp1 cells with Leishmania donovani results in
modulation of expression of a subset of chemokines and a chemokine
receptor. Scand. J. Immunol.57: 366-374.
Sengupta, K., PK Ghosh, S Ganguly, P
Das, TK Mitra and KN Jalan. 2002. Identification of Entamoeba
histolytica antigens in circulating immune complexes in amoebiasis
patients. Journal of Health, Population and Nutrition. 20:
Sengupta, S., A Akbar, P Mukhopadhyay, S
Ganguly, P Sen and P Das. 2000. Role of Excretory-Secretory
Products of E. histolytica in Human Amoebiasis. Archives of medical
research. 31-4: S226-S228.
Mukhopadhyay, P., S Sengupta, A Akbar, K
Sengupta, S Bhattacharya, A Debnath, S Ganguly and P Das. 2000.
Characterization of Plasma Membrane Associated Antigens of Diagnostic
and Prophylactic Importance in Entamoeba histolytica. Archives of
medical research 31-4: S21-S22.
Dibyendu Raj, Sanjib kumar Sardar and Sandipan Ganguly. Giardia,
Giardiasis and its zoonotic transmission. Book Chapter published
in Advances in medico veterinary parasitology, an Indian
perspective, edited by Arun Yadav, Veena Tandon and S L Hoti,
Page 22-40, 2018, Published by Panima Publishing Corporation,
New Delhi, India.
Sujit K. Bhattacharya, Ajanta Ghosal, Sudeshna Ganguly, Sandipan
Ganguly, Sabahat Azim and Shanta Dutta. Visceral Leishmaniasis.
Book chapter published in Leishmania as re emerging disease.
Edited by F. Afreen. Page 17-26 . 2018, Published by Intech
open, London, UK
Giardia and Giardiasis: An Overview On Recent Developments. Book chapter published in The Handbook of Microbial
Bioresources, edited by V K Gupta, G D Sharma, M G Tuohy, R Gaur. Page 211-227, June 2016. Published by CABI,
Ganguly S. Amoebiasis. 2015. Book chapter in Biology of foodborne parasites. Edited by Lihua Xiao,
Una Ryan and Yaoyu Feng. Taylor & Francis, USA. 2015
Bhattacharya SK and S Ganguly. Cholera. 2015. Book Chapter in API Textbook of Medicine. Edited by Y P Munjal.
Sandipan Ganguly. Amoebiasis. 2015. Book
chapter in Biology of foodborne parasites. Edited by Lihua Xiao,
Una Ryan and Yaoyu Feng. Taylor Francis, USA.
Sujit K Bhattacharya and Sandipan Ganguly.
Cholera. 2014. Book Chapter in API Textbook of Medicine. Edite by
Y P Munjal.
Sandipan Ganguly and Sumallya Karmakar.
Electroporation of snoRNA in Giardia lmblia. Microscopy: advances
in scientific research and education (A. Mêndez - Vilas, Ed.).
Formatex, Spain, 2014
Mukherjee AK, P Chowdhury, MK Bhattacharya, T van
Gool, T Nozaki and S Ganguly. 2011. TFT a novel stool collection
procedure for enhanced microscopical detection of enteric parasites: First
trial among parasite burden population in Kolkata. Book Chapter in
Microscopy - Science Technology Applications and Education (MICROSCOPY
BOOK SERIES - Number 4), Chapter 295. Published by Formatex, Spain.
Editor: A. Mêndez-Vilas, J. Dìaz
Sandipan Ganguly. 2007. Fluorescence Resonance
Energy Transfer using molecular beacon as a probe, a new approach for in
vivo macromolecular interaction study. Modern Research and Educational
Topics in Microscopy, published by Formatex, Spain.